Cardiologists
Take Vitamin E
and Recommend it to Their Patients
Washington,
DC—A
new survey of more than 300 cardiologists shows that many cardiologists take
vitamin E supplements themselves and also recommend vitamin E supplements to
their patients. The amount of vitamin E most commonly used or recommended is
400 International Units (IU).
The
survey found that three-fourths (75%) of cardiologists recommend vitamin E to
their patients at least some of the time, with 37% of cardiologists
recommending vitamin E "often" or "usually." When vitamin
E is recommended, the amount suggested is generally 400 IU, but 16% of the
physicians said they recommend 800 IU. About half of the cardiologists
surveyed (48%) said they personally use vitamin E supplements. The amount of
vitamin E used is most often 400 IU, but 13% said they use 800 IU.
This
survey shows that cardiologists are much more likely than the average American
to be taking vitamin E to protect the heart, presumably because cardiologists
are more aware of the scientific evidence. A recent survey by the Hartman
Group showed that 19% of American adults used a single-nutrient vitamin E
supplement. In comparison, the prevalence of vitamin E supplementation among
cardiologists is two-and-a-half times as high (48%).
"The
hypothesis that antioxidants such as vitamin E inhibit the atherosclerotic
process remains valid," said Michael Davidson, M.D., Director of
Preventive Cardiology at Rush Presbyterian-St. Luke’s Medical School in
Chicago and President of the Chicago Center for Clinical Research
(312-494-2221, mdavidson@protocare.com). "It makes sense to follow the
example of cardiologists who are choosing to protect themselves and their
patients now, while monitoring the results of new research as it
emerges."
Dr.
William A Pryor, an expert in the field of antioxidant research, recently
concluded that "there is now sufficient evidence to recommend modest
vitamin E supplementation (100 to 400 IU per day) as part of a general program
of heart-healthy behavior that includes a fruit- and vegetable-rich diet and
regular exercise." (Free Rad Biol & Med 2000;28:141-164) In
his extensive article, Dr. Pryor reviews and critiques all the available
evidence on vitamin E and heart disease, including animal and laboratory
studies as well as epidemiological data and several large clinical trials.
Eleven additional clinical trials are currently in progress, involving more
than 100,000 study participants. Dr. Pryor emphasizes that vitamin E "is
established as safe" at the levels being used in the clinical trials,
ranging from 100 to 800 IU per day. He notes that, in addition to its
heart-healthy effects, vitamin E also improves the immune function and
provides protection against some other diseases, such as prostate cancer.
A
report on dietary reference intakes for the antioxidant vitamins, released in
2000 by the Food and Nutrition Board of the Institute of Medicine, highlighted
promising research on vitamin E and heart disease but did not establish target
intakes for prevention of heart disease. The report acknowledged that current
research on the prevention of heart disease is heavily focused on preventing
the oxidation of LDL cholesterol. The report concluded that vitamin E does in
fact inhibit LDL oxidation and could also affect the risk of heart disease in
other ways, including effects on platelet aggregation, blood clotting, and the
characteristics of smooth muscle cells. The report called for further
research. On the issue of safety, the Food and Nutrition Board report said
supplemental vitamin E is safe for use by adults at levels up to 1000 mg per
day.
The
Food and Nutrition Board report indicated that the maximum degree of
protection against LDL oxidation requires dosages of vitamin E greater than
200 IU per day. These amounts cannot feasibly be obtained from conventional
foods, but can only realistically be obtained from dietary supplements. For
example, it would take 7 cups of peanuts or 19 cups of spinach to provide just
100 IU of vitamin E, and munching on peanuts delivers 166 calories per ounce,
according to a database compiled by the Department of Agriculture. In
contrast, a single soft gelatin capsule can provide 400 IU of vitamin E in an
economical, safe, easy-to-use, low-calorie form.
The
survey on vitamin E use among cardiologists was commissioned by the Council
for Responsible Nutrition (CRN), a trade association representing more than
110 companies in the dietary supplement industry, and was conducted by Psymed,
Inc., a marketing research firm based in Valley Forge, Pennsylvania.
Reader's Digest Reports on
Vitamin E: Truly a 'Health Care Miracle'
WASHINGTON, July 22 /PRNewswire/ -- Praise for Vitamin E, the "health
care miracle," is moving from scientific, medical and health publications
to America's mainstream, popular media -- including the latest issue of
Reader's Digest.
The August issue of the multi-million circulation magazine summarizes recent
research on Vitamin E and concludes:
"A wealth of research shows the potential benefits of this vitamin."
In an article by Anita Bartholomew, Reader's Digest reported that Vitamin E
supplements reduce the risk of heart disease, help prevent atherosclerosis
which can cause strokes, increase immune response, ease arthritis pains, and
delay the progress of Alzheimer's disease, among numerous health benefits.
The article reported on Vitamin E supplementation, noting that even a minimum
amount of 100 IUs (international units) from dietary sources would require
large amounts of fruits and vegetables, nuts and seeds.
"You'd have to eat nearly five pounds of spinach or four cups of
peanuts," the article said.
Dr. Nancy Snyderman, a California surgeon, was quoted as saying; "I used
tobelieve that if you ate a good diet, that was enough. But, frankly, you
don't get enough of the nutrient."
The article continued:
"If even half of the early findings about Vitamin E are approved in
continuing research, this vitamin can truly be called a health care
miracle."
The Reader's Digest listed "the evidence so far on how it (Vitamin E) may
help you:"
* Research at Tufts University in Boston showed, according to nutrition
researcher Jeffrey Blumberg, that Vitamin E can help people "be safer
from infectious disease -- colds, flu, tuberculosis."
* At the University of Texas Southwestern Medical Center in Dallas,
researchers found what they believe are reasons why Vitamin E can reduce
cardiac risk. Vitamin E helps prevent atherosclerosis, hardening of the
arteries, they concluded.
* A National Cancer Institute-supported study found a decreased rate of cancer
in test subjects who received combinations of vitamins, including Vitamin E,
according to scientists at Wayne State University in Detroit.
Vitamin E was also cited as benefiting smokers, slowing Alzheimer's disease,
and helping resist sunburn.